Leading scientists at the Heart Research Institute (HRI) are making strides in the fight against cardiovascular disease by developing a new blood test to identify individuals at risk. This breakthrough comes after researchers discovered a “good” gene that contributes to heart enlargement during exercise.
The groundbreaking research is spearheaded by Professor Julie McMullen, a prominent Australian heart scientist. She leads HRI’s Heart Muscle Group, which is dedicated to finding innovative methods for preventing and treating heart attacks and heart failure.
“Our aim is to replicate the beneficial effects of exercise in a diseased heart by leveraging the actions of these ‘good’ genes,” said Professor McMullen. “We plan to use this knowledge to create new medications that can lower the risk of heart disease and heart failure.”
In Australia, a heart attack occurs every 10 minutes, and cardiovascular disease claims a life every 12 minutes. Professor McMullen emphasized the widespread impact of heart disease, stating, “It can affect anyone. With rising obesity and type 2 diabetes rates, more people are experiencing heart issues at younger ages, which can lead to heart attacks and heart failure.”
She noted that existing medications often fall short in enhancing heart function and quality of life, underscoring the need for new therapies for those suffering from these conditions.
Additionally, HRI researchers are investigating the intersection of cardiology and oncology. They are studying how many cancer treatments can lead to cardiac complications, such as heart failure or atrial fibrillation, later in life.
“These complications may not manifest until many years after treatment,” Professor McMullen explained. “It is crucial for us to identify new biomarkers and therapeutic strategies in this complex and under-researched area.”
The work being done at HRI represents a significant advance in understanding cardiovascular health and developing effective interventions for those at risk.
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